ukwelashwa kokukhanya okubomvu kwezinja ezine-arthritis2

Ukwelashwa kokukhanya okubomvu (i-RLT), okwaziwa nangokuthi i-photobiomodulation, kuvele njengendlela ephawulekayo yokwengeza ekuvuseleleni kwezilwane ekuphatheni i-osteoarthritis ezinjeni. Lokhu kwelashwa okungangenisi umswakama kusebenzisa ubude obuthile bokukhanya ukuze kuveze izimpendulo zamaseli, okunikeza isu elihambisanayo nokuphathwa kwemithi okuvamile. Ukuhlanganiswa kwayo ohlelweni lokunakekelwa kwezinhlobo eziningi kungasiza ekuthuthukiseni induduzo yesiguli kanye nokuthuthukiswa kokusebenza kahle.

Izindlela kanye Nezinzuzo Zokwelapha Eziyinhloko

Ukusebenza kahle kwe-RLT kwezokwelapha kusekelwe ekusebenzisaneni kwayo kwe-photobiochemical ezingeni lamaseli. Uma kusetshenziswa ngaphakathi kwamafasitela ezokwelapha aqoshiwe, ukukhanya okubomvu ngokuvamile (630-660 nm) kwezicubu ezingaphezulu kanye ne-near-infrared (810-850 nm) kwezakhiwo ezijulile, ama-photon amuncwa yi-mitochondrial chromophores. Lokhu kumuncwa kuvuselela ukukhiqizwa kwamandla eseli (ATP), kuguqula izinhlobo ze-oxygen ezisabelayo, futhi kusebenze izindlela zokubonisa izimpawu. Izinzuzo zezokwelapha eziphumelayo ziphindwe kathathu:
I-Analgesia: Ukunciphisa ubuhlungu ngokunciphisa abaxhumanisi bokuvuvukala kanye nokuguqulwa kwezimpawu ze-neural.
Imiphumela Yokulwa Nokuvuvukala: Ukunciphisa ukuvuvukala nokuvuvukala ezingeni lamalunga, okunciphisa umthombo oyinhloko wokungakhululeki nokungasebenzi kahle.
Ukulungiswa Kwezicubu Okuthuthukisiwe: Ukukhuthaza ukwanda kwamaseli kanye ne-angiogenesis (ukwakheka kwemithambo yegazi emisha), okusekela indawo yokuphulukisa yezicubu ezithintekile.

Ngokubambisana, lezi zenzo zingaholela ekuthuthukisweni okulinganiselwe kokuhamba, ukuqina, kanye nokuzimisela kwenja ukuzibandakanya ekuzilolongeni okunqunyiwe kokwelapha, ngaleyo ndlela kwandisa izinzuzo zohlelo oluphelele lokuvuselela.

Ukuqinisekiswa Kwesayensi kanye Nesivumelwano Sezilwane

Ucwaningo olukhulayo lwezokwelapha lusekela ukusetshenziswa kwe-RLT ekuphatheni izimpawu ze-osteoarthritis yezinja. Izifundo eziningi zibonise ukwehla okuphawulekayo kwezibalo emazingeni obuhlungu kanye nokuzuza okulinganiselwe ekulinganisweni kwezinhloso njengokuhlaziywa kwepuleti lamandla (ukulinganisa isisindo) kanye nobubanzi bokunyakaza. Umphakathi wezilwane uvumelana kakhulu nenani lawo njengethuluzi eliphephile nelisebenzayo lokulawula ubuhlungu kanye nokuthuthukisa ikhwalithi yokuphila, okungenza ngezinye izikhathi kube lula ukunciphisa umthamo noma imvamisa yemithi engeyona i-steroidal anti-inflammatory (NSAIDs).

Nokho, kubalulekile ukuhlukanisa phakathi kokuphathwa kwezimpawu nokuguqulwa kwesifo. Nakuba izifundo ze-in vitro ziphakamisa ukuthi kungenzeka ukuvikela i-chondrosis noma ukulungiswa kwe-cartilage, ubufakazi obuqinisekile be-in vivo obuqinisekisa i-RLT njengomuthi we-osteoarthritis oguqula izifo (i-DMOAD) ezigulini zezokwelapha buseyindawo yophenyo olusebenzayo. Ngakho-ke, indima yayo yamanje iqiniswe ngokuqinile njengendlela eqinile yokuthuthukisa ukusebenza ngaphakathi kwesu lokuphatha impilo yonke.

Iphrothokholi, Ukuphepha, kanye Nezingqinamba

Ukusetshenziswa okuphephile nokuphumelelayo kwe-RLT kuncike ekunamatheleni ezimisweni ezimisiwe kanye nokuqwashisa ngeziphambeko. Ukwelashwa kufanele kuqalwe njalo ngaphansi kokuqondisa kwezilwane ukuqinisekisa ukuxilongwa kanye nesigaba se-arthritis.
Ukukhethwa Kwedivayisi: Sebenzisa kuphela amadivayisi ebanga lezilwane akhipha ubude besikhathi sokwelapha obuqinisekisiwe ngobuningi bamandla obufanele.
Indlela Yokusebenzisa: Inqubo evamile ihilela ukufaka idivayisi ngqo esikhumbeni (ethintaneni noma eduze kokuthintana) emalungeni athintekile imizuzwana engama-30-60 endaweni ngayinye, ngokuvamile kanye noma kabili ngosuku. Ubude obuqondile kanye nemvamisa kufanele kulungiselelwe isiguli ngasinye.
Izimo Ezibucayi Zokungalungi: Ukwelashwa kumele kugwenywe ngenxa yomdlavuza osebenzayo, indlala yegilo, amehlo (ngisho noma evaliwe), kanye nama-growing plate ezilwane ezingakavuthwa. Kufanele kuqashelwe ukuvela kwamathambo.
Iphrofayili Yokuphepha: Imiphumela emibi ayivamile kakhulu uma kulandelwa imigomo. Izikhathi kufanele ziqashwe ukuze kutholakale noma yiziphi izimpawu zokungakhululeki, futhi ukwelashwa kufanele kumiswe uma kubonakala noma yikuphi ukusabela okubi.

Ukuhlanganisa Ukuphathwa Kwekhaya Ehlelweni Lokunakekelwa

Kubanikazi abaphishekela ukwelashwa ekhaya, indlela ehlelekile nenolwazi ibaluleke kakhulu.
Ubambiswano Lwezilwane: Hlela isisekelo esicacile nodokotela wezilwane wakho, ongancoma idivayisi efanelekile kanye nenqubo yokwelashwa kokuqala.
Isimiso Esiqhubekayo: Hlanganisa izikhathi zokwelapha ezimfushane ngokuthula ohlelweni lwansuku zonke, uvame ukuzihlanganisa nokuqinisa okuhle njengokuhlikihla okuthambile.
Ukuqapha Okuhlosiwe: Landela izinkomba ezicashile neziqondile zentuthuko njengokulula kokuvuka ekuphumuleni, ukuzimisela ukukhuphuka izitebhisi, noma isikhathi sokwanda komsebenzi, kunokulindela "ukwelashwa" okumangalisayo.
Ukuhlanganiswa Okuphelele: I-RLT isebenza kahle kakhulu njengengxenye eyodwa yohlelo olunezindlela eziningi oluhlanganisa ukuphathwa kwesisindo, ukuvivinya umzimba okulawulwayo, ukwesekwa kokudla okunempilo (isb., izithasiselo zamalunga), kanye, uma kunqunyiwe, nemithi yezokwelapha.

Ukuhlaziywa Kwezindleko Nezinzuzo kanye Nokulindela Okungokoqobo

Inani le-RLT, kungakhathaliseki ukuthi linikezwa emtholampilo noma ekhaya, lidlula ukutshalwa kwezimali kokuqala. Izinzuzo ezingaba khona zesikhathi eside zifaka phakathi ukuthembela okuncishisiwe emithini ebiza kakhulu kanye nemithi evikela amathumbu ehambisana nayo, kanye nemiphumela ethuthukisiwe evela ekuvuselelweni ngokomzimba ngenxa yokuthobela okungcono isiguli. Kodwa-ke, impendulo yomuntu ngamunye iyahlukahluka; ezinye izinja zibonisa intuthuko ephawulekayo, kanti ezinye zithola izinzuzo ezicashile nezisekelayo.

Ukuphatha okulindelwe ngumnikazi kubalulekile. Impumelelo ivame ukuchazwa yizinzuzo eziqongelelekayo ezingeni lenduduzo nomsebenzi phakathi kwamasonto kuya ezinyangeni. Imibiko emfushane iyahlukahluka, igcizelela ukuthi i-RLT iyithuluzi elingeziwe, hhayi ikhambi elizimele. Ukusebenza kwayo okukhulu kutholakala ngaphakathi "kwesistimu yokunakekelwa kwemvelo," kuhambisana nezinye izici eziyisisekelo zokuphathwa kwamathambo ngaphansi kwesiqondiso sezilwane esiqhubekayo.