ukwelashwa kokukhanya okubomvu kwenja2

I-Photobiomodulation (PBM) yakha isimiso sesayensi esiyinhloko ngemuva kokwelashwa kokukhanya okubomvu kwezinja. Le ndlela isebenza ngokuletha ubude bamaza okukhanya okuqondiwe, ikakhulukazi ngaphakathi kwe-spectra ebomvu (~660 nm) kanye ne-near-infrared (~850 nm), ezicutshini zesilwane. Lawa mandla e-photonic amuncwa yi-chromophores ye-mitochondrial, ekhuthaza ukwenziwa kwe-adenosine triphosphate (ATP). Ukwanda okubangelwa yi-metabolism yamaseli kusheshisa izindlela zokubuyisela zangaphakathi, kunciphisa izindlela zokuvuvukala, futhi kuguqula izibonakaliso ze-nociceptive ezingeni eliyisisekelo. Ukusebenza kahle kokwelapha kuncike ekufinyeleleni ukungena okwanele kwe-photonic ukuze kufinyelelwe ezicutshini eziqondiwe, kugcizelela isidingo samadivayisi asebenzisa la ma-wavelength aqinisekisiwe futhi alethe umthamo olinganiselayo nosebenzayo.

Imininingwane Ebalulekile Yokukhetha Idivayisi

Ukuthola idivayisi enamandla okwelapha asemthethweni kudinga ukuhlolwa okuqinile kwemingcele yayo yobuchwepheshe. Okubaluleke kakhulu phakathi kwalokhu amaza okukhanya, okumele angene ngaphakathi kwebanga eliqinisekisiwe ngokwezokwelapha elingu-630680 nm (obomvu) kanye no-800880 nm (eduze kwe-infrared). Okubaluleke ngokulinganayo ukukhanya kwedivayisi (ubuningi bamandla), ngokuvamile okudingeka kube phakathi kuka-50100 mW/cm, ukuqinisekisa ukulethwa komthamo wamandla owanele (olinganiswa ngama-Joules/cm) ngaphakathi kwesikhathi sokwelashwa esisebenzayo. Amadivayisi anezimvume zomthetho, njengemvume ye-FDA 510(k) yezinkomba ezithile zezilwane, anikeza izinga eliphakeme lokuthembeka mayelana nokuphepha kwawo kanye nokuvumelana komkhiqizo uma kuqhathaniswa nemikhiqizo yezempilo ejwayelekile.

Ukuhlanganisa Umklamo Nokusetshenziswa Kokunamathela Ekwelashweni

Imininingwane yobuchwepheshe kumele ihambisane nezici zokuklama ezisebenza kahle nezisebenzayo ukuze kube lula ukusebenzisa njalo, ngaphandle kokucindezeleka. Isici sesimo sedivayisi kufanele sihambisane nesimo sengqondo sesiguli senja kanye nendawo yokwelashwa okuqondiswe kuyo; ama-pad aguquguqukayo avumela izikhathi zokumboza okubanzi, kuyilapho izinduku eziphathwayo zivumela ukusetshenziswa okunembile, okusendaweni. Izici ezifana nama-timer ahlanganisiwe azenzakalelayo, ukusebenza ngaphandle kokuthinta, kanye nokusebenza okuthule kuthuthukisa kakhulu ukusetshenziswa kanye nokuhambisana nomnikazi, okubalulekile ekufinyeleleni imiphumela yokwelapha yesikhathi eside ngaphakathi kohlelo lokunakekelwa oluhlelekile noluqondiswa udokotela wezilwane.

Ukusungula Iphrothokholi: Ukuphepha, Ukulinganisa, kanye Nokusetshenziswa

Ukusungulwa kohlelo lokwelapha oluphephile nolusebenzayo akunakuxoxiswana ngakho. Le nqubo kumele iqale ngokubonisana okuphelele nodokotela wezilwane ukuze kutholakale ukuxilongwa okunembile nokuhlola ukungavumelani, ikakhulukazi i-occult neoplasia. Impumelelo yokwelapha ihlotshaniswa ngokwemvelo nomthamo oqondile, okuwumsebenzi wokukhanya nobude besikhathi sokwelashwa. Izinqubo kufanele zihlukaniswe ngokuhlukile: izindlela zomthamo ophansi zingase zisekele impilo enhle jikelele, kuyilapho izindlela zomthamo ophezulu, eziqondene nezimo ezithile (isb., ze-osteoarthritis) kumele zinqunywe udokotela wezilwane. Indlela yokusebenzisa kumele ivumelane nenja ngayinye, kucatshangelwa izici ezifana nombala wesikhumba kanye nobuningi, inhloso yokwakheka komzimba, kanye nokubekezelela ukuziphatha ukuqinisekisa ukulethwa kokukhanya okuhle.

Ukuhlolwa Okungokoqobo Kwemiphumela Yokwelapha

Ukuhlolwa okulinganiselayo kokwelashwa kokukhanya okubomvu kudinga ukuhlukanisa izinzuzo ezisekelwe ebufakazini ezimangalweni ze-hyperbolic. Idatha yezokwelapha eqinile isekela ukusetshenziswa kwayo okungeziwe ezimweni ezithile ezifana ne-osteoarthritis yenja, okubonisa ukuthuthuka okulinganiselwe kokuhamba kanye namaphuzu obuhlungu. Kodwa-ke, ukusebenza kahle akuyona yonke indawo futhi kuncike ngokuphelele ekulinganisweni okufanele kanye nokukhethwa kwecala okufanele. Imiphumela emibi engaba khona mincane ngokusetshenziswa okufanele, kodwa ingozi enkulu isekuvuseleleni isimo esingatholakali. Ngakho-ke, ukulandelela imiphumela okuqondile njengokusetshenziswa kwemithi, amazinga omsebenzi, kanye nokusebenza emisebenzini ethile kubalulekile ukuqinisekisa izinzuzo kanye nokuqondisa ukulungiswa kwephrothokholi ngaphansi kokuqashwa kwezilwane.